P | Bats/Throws: R/R | 6' 1" 220 lbs | Age: 22
Draft: 2022 | Rd. 11, No. 330, San Diego Padres | Combine Academy
MLB Pipeline Rank
W L ERA G GS SV IP SO WHIP
2025 3 12 5.69 22 22 0 91.2 70 1.76
Career Minors 10 19 4.30 50 46 0 209.1 199 1.50
G W-L ERA IP SO WHIP
2025 22 3-12 5.69 91.2 70 1.76
Career Minors 50 10-19 4.30 209.1 199 1.50

Standard Minor League Pitching Statistics

SeasonTmLGLWLERAGGSSVIPHRERHRBBSOWHIP
2023 2 Teams Minors 0 1 2.19 4 4 0 12.1 10 6 3 1 5 18 1.22
2023 ACL Padres ACL ROK 0 0 9.00 1 1 0 1.0 1 1 1 0 1 1 2.00
2023 Lake Elsinore Storm CAL A 0 1 1.59 3 3 0 11.1 9 5 2 1 4 17 1.15
2024 2 Teams Minors 7 6 3.33 24 20 0 105.1 91 45 39 4 46 111 1.30
2024 Lake Elsinore Storm CAL A 5 3 3.00 17 13 0 72.0 56 27 24 2 29 89 1.18
2024 Fort Wayne TinCaps MID A+ 2 3 4.05 7 7 0 33.1 35 18 15 2 17 22 1.56
2025 Fort Wayne TinCaps MID A+ 3 12 5.69 22 22 0 91.2 110 67 58 8 51 70 1.76

Scouting Report

2025

Scouting grades: Fastball: 50 | Slider: 50 | Changeup: 45 | Control: 45 | Overall: 40

A Wake Forest commit out of North Carolina, Lowe was San Diego’s first Day 3 pick in 2022 and signed for $400,000, getting closer to fifth-round money as an 11th-round pick. He made only four starts in his first full season because of shoulder problems but thankfully avoided the injured list entirely in his age-21 campaign. He was a California League end-of-season All-Star after posting a 3.00 ERA and a 1.18 WHIP with 89 strikeouts in 72 innings for Single-A Lake Elsinore and finished out the year with seven starts in High-A Fort Wayne.

Throwing from the lower range of a three-quarters delivery, the sturdy 6-foot-1 right-hander ran his fastball up to 97 mph last season and generally sat 92-95. There was some tailing action on the pitch as he tended to land it up and armside. His 79-82 mph slider played well nicely off the heat, dropping just as it reached the plate to fool batters to his gloveside. The slider had a 44 percent whiff rate on its own, though it hasn't played nearly to that standard in 2025. An 85-87 mph changeup didn’t get much chase outside of the zone, and lefties handled Lowe much better than their right-handed counterparts as a result.

Lowe throws enough strikes to keep him in Minor League rotations for now, but there isn’t a ton of projection left in his frame. The fastball-slider combination should work in shorter stints if he ever needs to head to the bullpen, and after a healthy 2024, there is certainly an arrow pointed up next to his name.


2024

Scouting grades: Fastball: 55 | Slider: 55 | Changeup: 45 | Control: 50 | Overall: 45

San Diego area scouts believed enough in Lowe, who wasn’t on many top radars as a Wake Forest commit out of Combine Academy in North Carolina, to push to make him the club’s first Day 3 pick in 2022. Using savings from earlier rounds, the organization signed the right-hander for $400,000, giving him closer to fifth-round money. Lowe started three games for Single-A Lake Elsinore in April but was shut down due to shoulder problems, and those issues arose again after he made an Arizona Complex League rehab start.

Lowe has good deception in his sturdy 6-foot-1 frame and can run his fastball up to the mid-90s with some explosiveness up in the zone. With some tailing action, the fastball is at its best when he’s locating it armside. He can plop his slider into the zone for a called strike against anyone sitting on the high heat, or he can get chases down and gloveside when needed too. His changeup could be average in time with more development but looked too firm at times as he dipped his toe into pro ball.

The righty threw a good amount of strikes when he was on the mound last season, but given his size already, there might not be a ton of projection remaining for his stuff to add another tick or two. The fastball-slider will play though as is, when healthy, and sticking to the mound will be Lowe’s biggest goal entering his age-21 campaign in 2024.


2023

Scouting grades: Fastball: 55 | Slider: 55 | Changeup: 50 | Control: 50 | Overall: 40

Hailing from Combine Academy in North Carolina, Lowe wasn’t exactly on many big radars coming into 2022, though he did have a commitment to pitch at Wake Forest. Padres area scouts, however, found a lot to like and pushed successfully enough for him to be part of the organization’s Draft class as its first Day 3 pick in the 11th round. Using some of the savings from senior signs in rounds 8-10, San Diego inked Lowe for $400,000, which is closer to fifth-round money. He made three starts for Single-A Lake Elsinore in 2023 before hitting the injured list with a shoulder issue.

The 6-foot-1 right-hander already touches the mid-90s with his fastball, often settling in a little below that, and can blow it by hitters up in the zone. His slider already shows promising sweep across the zone to give him a second above-average pitch, while he has the feel for at least an average changeup too, which is more than can be said for many prep arms.

Throwing the ball in the zone doesn’t look like it’ll be much of a problem for the hurler, at least at this stage in his career. However, as promising as the whole package is, there is some concern that his frame is close to maxed out, and considering he’ll already be in his age-20 season in 2023, he won’t have as long a route of development as other pitchers coming out of high school. It’s a more intriguing profile than is often found in the 11th round, and Lowe will be given every chance to justify San Diego’s early faith with rotation spots in the lower Minors.



Awards




Transactions

Team Date Transaction
09/22/2025 Fort Wayne TinCaps activated RHP Isaiah Lowe from the 7-day injured list.
09/10/2025 RHP Isaiah Lowe assigned to Peoria Javelinas.
09/02/2025 Fort Wayne TinCaps placed RHP Isaiah Lowe on the 7-day injured list.
03/06/2025 activated RHP Isaiah Lowe.
07/30/2024 RHP Isaiah Lowe assigned to Fort Wayne TinCaps from Lake Elsinore Storm.
07/30/2024 Fort Wayne TinCaps activated RHP Isaiah Lowe.
11/06/2023 Lake Elsinore Storm activated RHP Isaiah Lowe from the 60-day injured list.
08/22/2023 Lake Elsinore Storm sent RHP Isaiah Lowe on a rehab assignment to ACL Padres.
08/22/2023 Lake Elsinore Storm sent RHP Isaiah Lowe on a rehab assignment to ACL Padres.
07/08/2023 Lake Elsinore Storm transferred RHP Isaiah Lowe from the 7-day injured list to the 60-day injured list.
05/05/2023 Lake Elsinore Storm placed RHP Isaiah Lowe on the 7-day injured list.
05/05/2023 Lake Elsinore Storm placed RHP Isaiah Lowe on the 7-day injured list.
04/03/2023 RHP Isaiah Lowe assigned to Lake Elsinore Storm from ACL Padres.
11/15/2022 RHP Isaiah Lowe assigned to ACL Padres.
08/01/2022 San Diego Padres signed RHP Isaiah Lowe.
09/15/2021 RHP Isaiah Lowe and assigned to Giants (NC '22).
07/13/2021 PG National 5 - Maroon activated RHP Isaiah Lowe.